Pentoxifylline Drug - How does Pentoxifylline Works?

Pentoxifylline Uses and Benefits of Pentoxifylline - Side Effects of Pentoxifylline

Type of Drug:

Hemorrheologic agent; a drug that improves blood flow.

How the Drug Works:

Pentoxifylline improves blood flow by reducing the thickness of the blood and improving red blood cell flexibility.

Uses:

To treat circulatory conditions in the arms and legs (eg, intermittent claudicating) that cause discomfort. It does not, however, cure these conditions.

Drug Interactions:

Tell your doctor or pharmacist if you are taking or planning to take any over-the-counter or prescription medications or dietary supplements while taking this medicine. Doses of one or both drugs may need to be modified or another drug may need to be prescribed. The following drugs and drug classes interact with this medicine: anticoagulants, oral (eg, warfare) theophylline (eg, Sio-Phyllin)

Side Effects:

Every drug is capable of producing side effects. Many patients experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects may include:

Digestive Tract: Stomach ache; nausea; vomiting; indigestion. Nervous System: Dizziness; headache.

Unlabeled Uses: Occasionally doctors may prescribe pentoxifylline for cardiovascular problems, circulatory and problems caused by diabetes, leg ulcers, sickle cell anemia, strokes, high altitude sickness, hearing problems, eye circulation disorders and Reynaud syndrome.

Precautions:

Do not use in the following situations: allergy to pentoxifylline, caffeine, therapy line or theo bromine cerebral and/or retinal bleeding

Use with caution in the following situations: arteriosclerosis (hardening of the arteries) kidney disease peptic ulcers surgery, recent

Pregnancy: Adequate studies have not been done in pregnant women, or animal studies may have shown a risk to the fetus. Use only if clearly needed and potential benefits outweigh the possible hazards to the fetus.

Breastfeeding: Pentoxifylline appears in breast milk. Consult your doctor before you begin breastfeeding.

Children: Safety and effectiveness in children have not been established. Lab tests or exams may be required to monitor therapy. Be sure to keep appointments. Tests may include prostration time and exams for bleeding (eg, hematocrit/hemoglobin).

Guidelines for Use:

  • Use exactly as prescribed.
  • Take 1 tablet, three times daily with meals. A lower dose may be necessary if side effects occur. Consult your doctor.
  • Do not crush, chew or break tablet.
  • If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose in order to “catch up” (unless advised to do so by your doctor). If more than one dose is missed or it is necessary to establish a new dosage schedule, contact your doctor or pharmacist.
  • Improvement may take 2 to 4 weeks to notice and up to 8 weeks for maximum relief.
  • If severe indigestion, nausea, vomiting, nervousness, dizziness or head­ache occur, contact your doctor immediately.
  • May cause dizziness. Use caution while driving or performing other tasks requiring alertness, coordination or physical dexterity.
  • Store at room temperature (59° to 86°F). Protect from light.


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